Search results for "reference limit"

showing 3 items of 3 documents

Definition of the upper reference limit of glycated albumin in blood donors from Italy.

2017

Abstract Background: Glycated Albumin (GA) has been proposed as a short-term indicator of glycemic homeostasis. The aim of this study is to describe the distribution of GA in a large sample of blood donors from Italy to evaluate whether demographic features, namely age and sex, could influence GA levels and define specific reference limits. Methods: The study included 1334 Italian blood donors. GA was measured using an enzymatic method (quantILab Glycated Albumin, IL Werfen, Germany). The upper reference limit (URL) was calculated using the non-parametric percentile method. Results: A modest, although significant, increase of GA was observed in relation to age (p<0.001), especially in ma…

AdultGlycation End Products AdvancedMalemedicine.medical_specialtyPercentileAdolescentClinical BiochemistryPopulationSerum albuminEnzyme Assay030209 endocrinology & metabolismBlood Donors030204 cardiovascular system & hematology03 medical and health sciencesYoung Adult0302 clinical medicineGlycated albuminReference ValuesInternal medicineDiabetes mellitusmedicineblood donors; diabetes; glycated albumin; reference limit; Adolescent; Adult; Aged; Enzyme Assays; Female; Humans; Italy; Male; Middle Aged; Reference Values; Serum Albumin; Young Adult; Blood Donors; Clinical Biochemistry; Biochemistry (medical)HumansReference ValueGlycated Serum AlbuminYoung adulteducationSerum AlbuminGlycemicAgedEnzyme Assayseducation.field_of_studydiabetesbiologyBlood Donorbusiness.industryBiochemistry (medical)General MedicineMiddle Agedreference limitmedicine.diseaseLarge sampleItalydiabetebiology.proteinglycated albuminFemalebusinessHumanClinical chemistry and laboratory medicine
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Establishing the upper reference limit of Galectin-3 in healthy blood donors

2017

Introduction Galectin-3 (Gal-3) is an independent predictor of poor outcomes and mortality in patients with heart failure (HF). Thus, it has been proposed as a reliable prognostic biomarker for HF. The definition of reference intervals is mandatory for interpreting the findings of experimental studies and encouraging the routine use of biomarkers in clinical practice. To date, no study assessed the reference intervals of Gal-3 and identified the biological variables that affect its concentration in a well-defined healthy population. The aim of this study was to determine the upper reference limit (URL) of Gal-3 in a highly reliable population of healthy subjects. Materials and methods We re…

AdultMalePercentilemedicine.medical_specialtyBlood donorAdolescentGalectin 3PopulationClinical BiochemistryBlood DonorsHeart failure030204 cardiovascular system & hematologyYoung Adult03 medical and health sciences0302 clinical medicineInternal medicineNatriuretic Peptide BrainmedicineHumansGalectin-3Prognostic biomarkergalectin-3; blood donors; heart failure; reference values; upper reference limit (URL)educationAgedImmunoassayeducation.field_of_studybusiness.industryHealthy populationTroponin IBiochemistry (medical)Healthy subjectsMiddle Agedreference valuesmedicine.diseaseOriginal PapersHealthy VolunteersReference intervals030220 oncology & carcinogenesisHeart failurePopulation studyFemaleUpper reference limit (URL)businessBiomarkersReference valueGlomerular Filtration Rate
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Acute pancreatitis in children. An Italian multicentre study

2002

Abstract Aim . To evaluate the clinical, morphological and aetiological aspects of acute pancreatitis in children in Italy. Patients . The hospital records of 50 consecutive patients with acute pancreatitis observed in 5 Italian Pediatric Departments were reviewed. Results . A total of 25 males and 25 females (median age 10.5 years, range 2–17) were studied. Of these patients, 48 (96%) had abdominal pain. The pancreatitis was associated with biliary disease in 10 patients (20%); it was due to viral infection in 6 patients (12%), pancreatic duct abnormalities in 4 (8%), familial chronic pancreatitis in 3 (6%), trauma in 5 (10%) and other causes in 5 (10%); the pancreatitis was of unknown ori…

Italy/epidemiologyMalemedicine.medical_specialtyAbdominal painURLSettore MED/09 - Medicina Internaacute pancreatitisBUNupper reference limitDiseasePancreatitis/epidemiologyGastroenterologyC-reactive proteinBiliary diseaseSettore MED/38 - Pediatria Generale E SpecialisticaInternal medicineMedicineHumansPancreatitis/etiologyChildblood urea nitrogenRetrospective StudiesPancreatic ducthuman immunodeficiency virusHepatologybiologybusiness.industryC-reactive proteinGastroenterologyHIVAcute Disease Child Female Humans Italy/epidemiology Male Pancreatitis/diagnosis Pancreatitis/epidemiology* Pancreatitis/etiology Retrospective Studiesacute pancreatitisBUN; blood urea nitrogen; CRP; C-reactive protein; HIV; human immunodeficiency virus; URL; upper reference limitmedicine.diseaseSurgerymedicine.anatomical_structureItalyPancreatitisAcute DiseaseEtiologybiology.proteinAcute pancreatitisPancreatitisFemalemedicine.symptomCRPbusinessPancreatitis/diagnosiHuman
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